New Study Proposal Toolkit
The identification of new research initiatives, the creation of innovative and unique research projects and the nurturing of new investigators and coordinators are the cornerstones of the Parkinson Study Group's collaborative efforts and are essential to our goal of advancing knowledge.
The PSG encourages projects which include retrospective analyses of PSG clinical trial databases. We have compiled a list of all the PSG databases that are available. Please see the PSG Database Inventory and the PSG Data Sharing Resources for more information. More specific study-related information can be found in two inventories of assessments: A list of measures included in each study can be found in the Database Inventory Assessments Spreadsheet, and more detailed information about variable coding and frequency of collection can be found in the Variable Collection and Coding Inventory.
Proposing investigators should review prior PSG studies to see if their question has already been addressed and explain why their project should go forward if it appears similar to another. Click to download PSG Proposals Approved/Awarded for detailed information.
How to Prepare & Submit a Proposal
The documents below establish the procedures and assist with the planning for new study proposals to be evaluated, reviewed and considered for approval as formal Parkinson Study Group projects. The same documents are to be used when applying for the Mentored Clinical Research Award.
Click on the links to download any of the following:
Attachment 1 - Application Face Page (2 pages)
Attachment 2 - Example of Protocol Template
Template of Protocol Synopsis and Schedule of Activities (doc)
Attachment 3 - Checklist (1 page)
To review examples of projects that retrospectively analyzed PSG clinical trial databases, please see the following publications:
- Factors predictive of the need for levodopa therapy in early, untreated Parkinsons disease.
- Levodopa improves motor function without impairing cognition in mild non-demented Parkinsons disease patients.
- Freezing of gait in PD: Prospective assessment in the DATATOP cohort.
- Placebo-associated improvements in motor function: Comparison of subjective and objective sections of the UPDRS in early Parkinson’s disease.
- Quality of life in early Parkinson’s disease: Impact of dyskinesias and motor fluctuations.
- Survival in Parkinson disease: Thirteen-year follow-up of the DATATOP cohort.
- The Need for Levodopa as an End Point of Parkinson's Disease Progression in a Clinical Trial of Selegiline and a-Tocopherol
Below are two examples of successful mentored research award proposals. Click on a link to download the file.
- PSG Mentored Clinical Research Award: "Behavioral Treatments for Anxiety in Parkinson's Disease (BehTA-PD): A Pilot Study" by Jessica S. Calleo, PhD, Assistant Professor of Psychiatry and Behavioral Sciences, Baylor College of Medicine.
- PSG Mentored Clinical Research Award: "A Pilot Study of Balance and Vitamin D in Persons with PD" by Amie L. Peterson, MD, Assistant Professor, Oregon Health & Science University.
For questions about the PSG New Study Proposal Toolkit, or for problems accessing the PDF files or hyperlinks, please email Roseanna Battista.
Featured link: Parkinson’s Foundation Patient Engagement.
The Parkinson’s Foundation can match you with trained Research Advocates and recommend how they can help in all research studies — from preclinical to phase IV studies and in observational and non-pharmacological interventional trials.
If you are interested in working with a Parkinson’s Foundation Research Advocate, please contact Karlin Schroeder, Senior Director, Community Engagement at email@example.com or our Helpline at 1-800-4PD-INFO (473-4636). We can discuss projects you have in mind, as well as suggest ways to collaborate with Research Advocates to improve your studies and speed the research process.